CircO2 Review, Legit or a scam?
CircO2 Review: Is This “Youth Molecule” Lozenge the Key to Energy After 50?
As we age, specifically after crossing the 50-year mark, the complaints often become universal: energy levels aren’t what they used to be, “senior moments” of forgetfulness become frequent, and blood pressure readings start to creep up. For years, the medical community and supplement industry have pointed toward one culprit: the decline of Nitric Oxide.
You might have heard of Nitric Oxide (NO) as the molecule responsible for healthy blood flow. However, standard solutions like L-Arginine pills or drinking gallons of beet juice often fail to deliver results for older adults. This is where a product called CircO2 claims to differ. In this comprehensive CircO2 review, we will dissect this supplement from Advanced Bionutritionals to see if its unique delivery system—a dissolving lozenge—truly solves the absorption problem that plagues other supplements.
In this deep dive, you will find a breakdown of the science behind it, a brutal look at the pros and cons, and a direct answer to whether this premium supplement is worth your retirement savings or just another hype.
Important Note: This is just a comprehensive unbiased reveiw, Click here to visit the CircO2 official website
Table of Basic Information about CircO2
Before we analyze the mechanism and efficacy, here is a quick-reference table summarizing the core details of the product.
| Feature | Details |
| Product Name | CircO2 |
| Manufacturer | Advanced Bionutritionals |
| Formulator | Dr. Greg Eckel (Naturopathic Physician) |
| Primary Purpose | Boost Nitric Oxide levels, improve circulation, & increase energy |
| Delivery Method | Quick-dissolve lozenges (Sublingual/Buccal absorption) |
| Key Ingredients | Beet Root Powder, Hawthorn Berry, L-Citrulline, Vitamin B12, Magnesium |
| Target Audience | Men and women over 50 experiencing fatigue or circulation issues |
| Flavor | Natural berry flavor |
| Prescription Required? | No |
| Price Range | $41.50 – $49.95 per box (depending on package size) |
| Guarantee | 90-Day “Down to the Last Lozenge” Money-Back Guarantee |
| Availability | Official Website Only (Not on Amazon/Walmart) |
What is CircO2?
CircO2 is a dietary supplement specifically formulated to address the drastic decline in Nitric Oxide production that occurs with aging. Research indicates that by the time you reach age 70, your body’s ability to produce Nitric Oxide may drop by up to 75%. This decline is often the “hidden cause” behind low energy, poor circulation, and cognitive fog.
Unlike traditional capsules or powders that you swallow, CircO2 is designed as a lozenge. It is produced by Advanced Bionutritionals, a company known for formulating high-grade supplements, and is endorsed by Dr. Greg Eckel, a Naturopathic Physician with over two decades of experience in regenerative medicine.
The core premise of CircO2 is not just to provide ingredients that contain nitrates, but to provide a delivery system that ensures those nitrates are actually converted into Nitric Oxide. The product positions itself as an “Oxygen Booster” for the body, aiming to open up narrowed blood vessels to allow nutrient-rich blood to flow freely to the heart, brain, and muscles.
How Does the CircO2 Work? (The Science Behind the Lozenge)
To understand why CircO2 is different, we must first understand why other supplements fail. This is the most critical part of our analysis.
The Problem with Regular Supplements
Most Nitric Oxide supplements rely on L-Arginine. While L-Arginine is a precursor to Nitric Oxide, it has a major flaw for seniors: the “Arginine Pathway” relies on a specific enzyme that stops working efficiently as you age. Furthermore, when you swallow an L-Arginine pill, it goes into your stomach, where stomach acids destroy a significant portion of the nutrient before it ever reaches your bloodstream. Studies suggest up to 75% of potency is lost during digestion.
The CircO2 “Salivary Pathway” Solution
CircO2 utilizes a completely different biological pathway known as the Nitrate-Nitrite-Nitric Oxide pathway.
- The MIT Discovery: The product relies on research (some attributed to scientists at MIT) discovering that the first step of Nitric Oxide production actually happens in the mouth, not the stomach.
- The Role of Bacteria: Friendly bacteria located on the ridges of your tongue are responsible for converting dietary nitrates into nitrites.
- Saliva Activation: When you swallow these nitrites in your saliva, they reach the stomach. Because they are already converted, the stomach acid doesn’t destroy them; instead, it converts them further into Nitric Oxide.
This is why CircO2 is a lozenge. By allowing the tablet to dissolve on your tongue, you are mixing the ingredients (Beet Root and Hawthorn) directly with the specific bacteria in your mouth needed to kickstart this chain reaction.
If you were to swallow CircO2 whole like a pill, it would likely be far less effective. This delivery method is scientifically sound and addresses the “absorption gap” that makes many other pills useless for people over 60.
Comparison: CircO2 vs. Traditional L-Arginine Pills
| Feature | CircO2 (Lozenges) | Standard L-Arginine (Pills) |
| Absorption Site | Mouth (Tongue/Saliva) | Stomach/Gut |
| Bioavailability | High (Bypasses digestion destruction) | Low (Degraded by stomach acid) |
| Effectiveness for Age 50+ | Optimized for aging bodies | Declines significantly with age |
| Speed of Action | Rapid (Minutes) | Slow (Requires digestion) |
| Nitric Oxide Pathway | Nitrate-Nitrite-NO Pathway | L-Arginine-NO Pathway |
CircO2 Ingredients: A Detailed Breakdown
A supplement is only as good as its components. In this section of our CircO2 review, we analyze the label to see if the dosages and choices justify the price point.
1. Beet Root Powder (The Nitrate Powerhouse)
Beetroot is the star ingredient. It is naturally high in nitrates. However, eating beets requires consuming massive amounts (pounds per day) to get a therapeutic effect, and the sugar content in beets can be an issue for some seniors. CircO2 uses a concentrated powder to deliver the nitrates without the bulk or excessive sugar. This ingredient is directly linked to improved stamina and lower blood pressure.
2. Hawthorn Berry (The Heart Hero)
This is a smart addition by Dr. Eckel. Hawthorn has been used for centuries in traditional medicine for heart health. Modern science suggests it acts as an “absorption booster” for Nitric Oxide. It helps relax blood vessels, which reduces the resistance against which the heart has to pump, thereby supporting healthy blood pressure levels.
3. L-Citrulline (The Superior Amino Acid)
While CircO2 avoids L-Arginine, it includes L-Citrulline. Why? Because L-Citrulline is converted into L-Arginine in the kidneys, bypassing the gut destruction problem. It provides a sustained release of Nitric Oxide over time. It is widely considered superior to L-Arginine for improving erection quality and athletic performance in older men.
4. Vitamin B12 (The Energy Vitamin)
The formula includes Vitamin B12 (likely in the form of Methylcobalamin or Cyanocobalamin). This is crucial because approximately 30% of adults over 50 have difficulty absorbing B12 from food due to reduced stomach acid. B12 deficiency mimics aging: fatigue, brain fog, and nerve issues. Adding this ensures the “energy boost” isn’t just from blood flow, but also from cellular energy production.
5. Vitamin C (The Protector)
Nitric Oxide is an unstable molecule; it degrades quickly. Vitamin C is a potent antioxidant that increases the bioavailability of Nitric Oxide by protecting it from oxidative stress. It essentially makes the Nitric Oxide “last longer” in your system.
6. Magnesium
Magnesium is essential for hundreds of bodily functions, including the relaxation of arterial walls. It works synergistically with Nitric Oxide to prevent blood vessels from constricting, further aiding in blood pressure management and heart rhythm stability.
Advantages of CircO2: The Benefits for the Golden Years
For those over 50, a supplement isn’t just about “feeling better”—it’s about maintaining independence and vitality. Based on the clinical claims and user feedback, here are the primary advantages:
- Rapid Action (The 20-Minute Window): Unlike many vitamins that take weeks to “build up” in your system, CircO2 is designed for immediate impact. Because it enters the bloodstream through the saliva/mouth pathway, many users report a noticeable “lift” in mental clarity and physical warmth (from improved circulation) within 20 to 30 minutes.
- Blood Pressure Support: This is perhaps the most significant benefit for seniors. By increasing Nitric Oxide, the smooth muscles in your arteries relax (vasodilation). This allows blood to flow with less resistance, which naturally helps keep blood pressure readings within a healthy, normal range.
- Brain Fog Clearance: The brain is the body’s biggest consumer of oxygen. When circulation is sluggish, memory lapses occur. CircO2 helps “flush” the brain with oxygenated blood, which can sharpen recall and focus.
- Stimulant-Free Energy: Many “energy boosters” are loaded with caffeine or Guarana, which can cause heart palpitations and “the jitters” in older adults. CircO2 provides energy by improving oxygen delivery at the cellular level, meaning no crashes and no shakes.
- Ease of Use: If you are tired of swallowing “horse pills,” the lozenge format is a breath of fresh air. It has a pleasant, slightly sweet berry taste and dissolves quickly.
Disadvantages of CircO2: A Critical Perspective
As many readers of this CircO2 review have asked, “Is there a catch?” Yes, there are a few considerations you should be aware of before purchasing:
- The Price Point: This is a premium product. At nearly $50 for a single box (one-month supply), it is significantly more expensive than generic beet powders or L-arginine capsules found at local pharmacies.
- The “Mouthwash” Conflict: This is a fascinating but annoying drawback. If you use strong antiseptic mouthwash (like Listerine), you might kill the very bacteria on your tongue required to activate CircO2. To get the full effect, you may need to switch to a natural, non-antiseptic toothpaste or mouthwash.
- Availability: You cannot find CircO2 at Walgreens, CVS, or Amazon. It is only available through the official Advanced Bionutritionals website. While this ensures you get a fresh product, it prevents you from “picking it up” during your weekly grocery run.
- Not a “Cure-All”: While it helps with blood pressure and circulation, it is a supplement, not a medication. It should not be used to replace prescription heart medications without a doctor’s supervision.
How to Use the CircO2? (The Correct Way)
To ensure you aren’t wasting your money, you must follow the specific delivery instructions. This isn’t a candy; it’s a delivery system.
- Do Not Swallow: Do not gulp the tablet down with water. This bypasses the salivary pathway and reduces effectiveness by up to 70%.
- The “Slow Dissolve”: Place one lozenge on your tongue or between your cheek and gum. Let it dissolve naturally. This usually takes about 2 to 5 minutes.
- Timing: Most users find it best to take one lozenge in the morning to kickstart their energy for the day. If you have a particularly active afternoon or an evening event, a second dose is safe, but for most, once a day is sufficient.
- The “Nitric Oxide Test”: Some packages come with (or allow you to buy) test strips. You can test your saliva before and 20 minutes after taking the lozenge to actually see the Nitric Oxide levels change on the strip.
Comparison: CircO2 vs. The Leading Competitors
To make this CircO2 review as honest as possible, we have to look at how it compares to the most famous “Beet” supplement on the market: SuperBeets.
| Feature | CircO2 | SuperBeets (Powder) | Generic L-Arginine |
| Form | Dissolvable Lozenge | Powder (Mix with water) | Capsule/Pill |
| Target Pathway | Salivary (Nitrate-Nitrite) | Digestive (Nitrate) | Urea Cycle (Arginine) |
| Added Nutrients | B12, Magnesium, Hawthorn | Just Beets / Vitamin C | Usually none |
| Taste | Berry (Pleasant) | Beety/Earthy | Neutral (Tasteless) |
| Convenience | High (Take anywhere) | Low (Needs a glass/water) | High |
| Price | High ($$$) | Medium ($$) | Low ($) |
| Scientific Focus | Seniors (50+) | General Athletes | General Health |
Where to Buy the CircO2?
There is only one safe place to purchase this supplement: the Advanced Bionutritionals Official Website.
Warning: You may see “CircO2” listed on eBay or third-party sellers on Amazon. Be extremely cautious. Because this product has a high resale value, counterfeiters often sell expired or fake versions in look-alike packaging. Furthermore, buying from third parties voids the 90-day money-back guarantee. When you buy from the official source, you are guaranteed:
- Potency and freshness.
- The 90-day “Down to the Last Lozenge” guarantee.
- Direct customer support from the manufacturer.
FAQs: Common Questions from Seniors
Q: Is CircO2 safe if I take blood pressure medication?
A: While the ingredients are natural, CircO2’s job is to relax blood vessels. If you are already taking medication that does this, your blood pressure could drop too low. Always show the ingredient list to your doctor before starting.
Q: Will it give me “the shakes” like an energy drink?
A: No. There is zero caffeine in CircO2. The energy comes from increased oxygen, not central nervous system stimulation.
Q: How many boxes should I start with?
A: Most people start with 3 boxes. This gives the body 90 days to fully adjust and provides a significant discount (and free shipping).
CircO2 Packages, Bonus, and Discount
One of the most important parts of any purchasing decision is understanding the value proposition. Advanced Bionutritionals has structured their pricing to reward those who are committed to long-term health improvements. Since Nitric Oxide levels need consistent support, the bulk packages offer the most significant savings.
Detailed Pricing Structure
When you complete your order, you aren’t just getting a bottle of pills. Here is what is included in your shipment:
- The CircO2 Lozenges: Each box contains a 30-day supply (30 lozenges) individually sealed in blister packs to ensure they don’t oxidize or lose potency before they reach your tongue.
- Instructional Guide: Clear directions on how to use the “salivary pathway” to maximize your results.
- The 90-Day “Down to the Last Lozenge” Guarantee: This is perhaps the most impressive “bonus.” Advanced Bionutritionals allows you to use the entire product. If you reach the end of your 90-day supply and don’t feel a surge in energy or see better blood pressure numbers, you can return the empty boxes for a full refund (minus return shipping). This effectively removes the financial risk for the senior consumer.
The “Dr. Greg Eckel” Factor: Who Is Behind This?
When we conduct a CircO2 review, we must look at the credibility of the endorser. Dr. Greg Eckel is not just a spokesperson; he is a Naturopathic Physician with over 23 years of experience. He is the founder of the Energy4Life Centers and has a background in Chinese Medicine and regenerative technologies.
His involvement suggests that the formula isn’t just a random mix of chemicals but a thought-out combination of botanical medicine (Hawthorn and Beet) and modern nutritional science (Citrulline and B12). However, it is always worth noting that Dr. Eckel is compensated for his endorsement, so while his credentials are solid, you should always weigh his advice against your own primary physician’s recommendations.
What to Expect: The Transformation Timeline
If you decide to try CircO2, what does the “recovery” of your Nitric Oxide levels actually look like?
- Day 1 (The First 20 Minutes): You may feel a slight warming sensation in your hands and feet as blood vessels begin to dilate. Some users report a “lifting” of the midday fog.
- Week 1-2: Energy levels usually become more “level.” Instead of the afternoon crash, you might find you have the stamina to finish gardening or go for that evening walk.
- Month 1: This is where blood pressure benefits typically become more apparent. As the arteries remain more relaxed throughout the day, the heart doesn’t have to work as hard.
- Month 3 (The Full Effect): By this point, the synergistic effects of Magnesium and B12 have helped stabilize nerve function and heart rhythm, while the constant presence of Nitric Oxide ensures your brain and muscles are optimally oxygenated.
Final Summary of Product Benefits
To recap, here is the “Master List” of what CircO2 aims to provide for the aging body:
- Renewed Energy & Stamina: Stay active without the dreaded afternoon fatigue.
- Sharper Cognition: Faster recall of names and dates; better focus during conversations.
- Cardiovascular Health: Support for healthy, doctor-approved blood pressure readings.
- Enhanced Mobility: Better blood flow to the joints can reduce stiffness and discomfort.
- Sexual Vitality: Improved circulation is the primary driver of performance and intimacy in both men and women.
- Better Sleep: When the body is properly oxygenated, it can enter deeper, more restorative sleep cycles.
Final Conclusion: Is It Worth It?
After analyzing every ingredient, the unique delivery system, and the customer feedback, we have reached the end of this CircO2 review.
The Verdict: If you are a senior who has tried “beet powders” or “arginine pills” with no luck, CircO2 is likely the solution you’ve been looking for. The science of the “salivary pathway” is a game-changer for people over 50 whose digestive systems no longer process standard supplements efficiently.
While the price is higher than generic alternatives, the combination of high-quality ingredients like Hawthorn Berry and L-Citrulline—plus the security of a 90-day empty-box guarantee—makes this a low-risk, high-reward investment in your longevity.
Who should buy it?
- Seniors struggling with persistent fatigue.
- Anyone looking for a natural way to support healthy blood pressure.
- People who hate swallowing large capsules.
Who should skip it?
- Those on a very tight budget who are already seeing results from raw beet juice.
- Anyone unwilling to give up antiseptic mouthwash (which kills the necessary bacteria).
In the world of anti-aging supplements, CircO2 stands out as a scientifically backed, easy-to-use, and highly effective tool for reclaiming the vitality of your younger years.
Final Checklist Before You Buy:
- Have you consulted your doctor about your current BP meds?
- Are you prepared to let the lozenge dissolve (not swallow)?
- Are you choosing the 3 or 6-box option to get free shipping?
If you’re ready to see what 200% more Nitric Oxide feels like, you can find the official order page at Advanced Bionutritionals. Thank you for reading our complete CircO2 review.